<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
94CY017_41 94CY017_41 Cyprus 1994 HIV1 A PBMC Genomic

Treatment History
Order Regimen Weeks
1 Unknown NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    K14R, S24H, I72V, A91T, E96D, L101I, T112V, S119P, T122I, T124A, K136Q, V201I, K215R, L234I S283G
>94CY017_41| codons 1-288
FLDGIDKAQEEHERYHSNWRAMAHDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPTETGQDTAYFILKLAGRWPVKVIHTDNGPN
FISATVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQRQITKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, G16E, M36I, R41K, L63A, H69K, K70R, L89M, T91V, I93L  
>94CY017_41| codons 1-99
PQITLWQRPLVTVKIEGQLKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QIAIEICGKRAIGTVLVGPTPVNIIGRNMLVQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
T215Y       V35T, T39K, S105A, D121H, K122E, I135T, I142V, K173S, Q174K, P176T, D177E, I178L, V179I, G196S, T200V, Q207A, R211K, V245K, T286A, E291D, V292I, I293V, P294T, E297K, A304E, E312T, G335D, R356K, M357R, G359S, A360T, V365I, A376T, T377M, A400T, T403A, V435A, V466I, D471E, Q480H, H483Y, D511E, K512R, L517I, S519N, Q524K, K527E, K530R, A534S, A554S  
>94CY017_41| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICKEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKAVTVLDVGDAYFSVPL
HEDFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNTELII
YQYMDDLYVGSDLEISQHRVKIEELRAHLLKWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVTLTKEAE
LELEENREILKTPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKRRST
HTNDIKQLTEAVQKITMESIVIWGKTPKFKLPIQKETWETWWAEYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIAGAETFYVDGAANRETKLGKAGYVTDRGRQKIVSLTETTNQKTELH
AIYLALQDSGLEVNIVTDSQYALGIIQAQPERSESEIVNQIIEKLIEKERVYLSWVPAHK
GIGGNEQVDKLVSSGIRKVL

References
Author Title Citation
Gao, F Evidence of two distinct subsubtypes within the HIV-1 subtype A radiation. ARHR, 2001