<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
61 LR061 U.S. 1990 HIV1 B PBMC MMC

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    E11D, E48Q, M50I, G106A, S119T, T124N, E157K, V201I, I203M, D256E, A265V  
>LR061| 1 | codons 1-288 | clone 1
FLDGIDKAQEDHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGQAIHGQVDCSPGI
WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFLLKLAARWPVKTIHTDNGTN
FTSNTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKKLKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDMIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSEIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
>LR061| 2 | codons 1-288 | clone 2
FLDGIDKAQEDHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGQAIHGQVDCSPGI
WQLDCTHLEGKIILVAVHAASGYIEAEVIPAETGQETAYFLLKLAARWPVKTIHTDNGTN
FTSNTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDMIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSEIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
>LR061| 3 | codons 1-288 | clone 3
FLDGIDXAQEDHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGQAIHGQVDCSPGI
WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFLLKLAARWPVKTIHTDNGTN
FTSNTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKKLKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDMIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSEIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
>LR061| 7 | codons 1-288 | clone 7
FLDGIDKAQEDHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGQAIHGQVDCSPGI
WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFLLKLAARWPVKTIHTDNGTN
FTSNTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKKLKKIIGQVRDQAEHLKTAVQMAV
FIHNF*REGGIGGYSAGERIIDMIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSEIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
>LR061| 8 | codons 1-288 | clone 8
FLDGIDKAQEDHEKYHSNWRAMASDFNPPPVVAKEIVASCDKCQLKGQAIHGQVDCSPGI
WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFLLKLAARWPVKTIHTDNGTN
FTSNTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKKLKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDMIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSEIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
>LR061| 9 | codons 2-288 | clone 9
LDGIDKAQEDHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGQAIHGQVDCSPGIW
QLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFLLKLAARWPVKTIHTDNGTNF
TSNTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKKLKKIIGQVRDQAEHLKTAVQMAVF
IHNFKRKGGIGGYSAGERIIDMIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAKL
LWKGEGAVVIQDNSEIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
>LR061| codons 1-288
FLDGIDKAQEDHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGQAIHGQVDCSPGI
WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFLLKLAARWPVKTIHTDNGTN
FTSNTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKKLKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDMIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSEIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED

References
Author Title Citation
Skinner, LM Analysis of a large collection of natural HIV-1 integrase sequences, including those from long-term nonprogressors. JAIDS, 1998