Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 61 | LD061 | U.S. | 1990 | HIV1 | B | PBMC | MMC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| E11D, E48Q, M50I, G106A, S119T, T124N, K160R, V201I, I203M, D256E, A265V |
| >LD061| 1 | codons 1-288 | clone 1 FLDGIDKAQEDHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGQAIHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFLLKLAARWPVKTIHTDNGTN FTSNTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKRIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDMIATDIQIKELQKQITKIQNFRVYYRDSRDPLWKGPAK LLWKGEGAVVIQDNSEIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED >LD061| 2 | codons 1-288 | clone 2 FLDGIDKAQEDHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGQAIHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFLLKLAARWPVKTIHTDNGTN FTSNTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKRIIGQVRDQAEHFKTAVQMAV FIHNFKRKGGIGGYSAGERIIDMIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK LLWKGEGAVVIQDNSEIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED >LD061| 3 | codons 1-288 | clone 3 FLDGIDKAQEDHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGQAIHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFLLKLAARWPVKTIHTDNGTN FTSNTVKASCWWAGIKQEFGIPYNPQSQGVVESMNKELKRIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDMIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK LLWKGEGAVVIQDNSEIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED >LD061| 4 | codons 1-288 | clone 4 FLDGIDKAQEDHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGQAIHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFLLKLAARWPVKTIHTDNGTN FTSNTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDMIATDIQTKELQKQITKIX~~~~~XRDSRDPLWKGPAK LLWKGEGAVVIQDNSEIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED >LD061| 5 | codons 1-288 | clone 5 FLDGIDKAQEDHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGQAIHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFLLKLAARWPVKTIHTDNGTN FTSNTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDMIATDIQTKELQKQITKIX~~~~~XRDSRDPLWKGPAK LLWKGEGAVVIQDNSEIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED >LD061| 6 | codons 1-288 | clone 6 FLDGIDKAQEDHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGQAIHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFLLKLAARWPVKTIHTDNGTN FTSNTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKRIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDMIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK LLWKGEGAVVIQDNSEIKVVPRREVKIIRDYGKQMAGDDCVASRQDED >LD061| codons 1-288 FLDGIDKAQEDHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGQAIHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFLLKLAARWPVKTIHTDNGTN FTSNTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKRIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDMIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK LLWKGEGAVVIQDNSEIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED |
References
| Author | Title | Citation |
| Skinner, LM | Analysis of a large collection of natural HIV-1 integrase sequences, including those from long-term nonprogressors. | JAIDS, 1998 |