<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
GHNJ196 GHNJ196 Ghana 2004 HIV1 CRF02_AG PBMC BC

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    K14R, S24N, V31I, L101I, K111R, T112V, T124A, T125A, G134D, I135V, V201I, T206S, T218I, L234I, R269K S283G
>GHNJ196| codons 1-288
FLDGIDKAQEEHERYHSNWRAMANDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVRVIHTDNGSN
FTSAAVKAACWWADVKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIASDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIKDYGKQMAGDDCVAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, K20I, E35E_K, M36V, N37E, R41K, H69K, K70R, L89M G17C
>GHNJ196| codons 1-99
PQITLWQRPLVTVRIGCQLIEALLDTGADDTVLEEVELPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, E36D, K46Q, D121H, K122E, I135V, S162A, K173T, Q174N, D177E, I178M, T200A, Q207E, R211K, P243H, V245E, A272P, K277R, T286A, E291D, V292I, I293V, P294T, S322A, I326V, G335D, R356K, M357K, G359S, A371V, I375V, V381I, K390R, T403M, E404D, E432D, D471E, Q480H, L491S, E514D, L517I, S519N, Q520L, Q524K, K527E, E529D, A534S, A554N, K558R T84P
>GHNJ196| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTDICTEMEKEGQISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRPQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
HEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTNNPEMVI
YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQHIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVTLTEEAE
LELAENREILKEPVHGVYYDPAKDLVAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKKRSA
HTNDVKQLTEVVQKVATESIIIWGKTPKFRLPIQKETWEAWWMDYWQATWIPEWEFVNTP
PLVKLWYQLEKDPIVGAETFYVDGAANRETKLGKAGYVTDRGRQKVVSLTETTNQKTELH
AIHLALQDSGSEVNIVTDSQYALGIIQAQPDKSDSEIVNLIIEKLIEKDKVYLSWVPAHK
GIGGNEQVDKLVSNGIRRVL

References
Author Title Citation
Tatsumi, M Infectious DNA clones of subtype G and CRF02_AG HIV-1 derived from Ghananian isolates. Direct Genbank Submission, 2006