<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
2931HA 2931HA Cameroon 2003 HIV1 G PBMC None

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    E10D, V31I, L101V, T112V, S119P, T122I, T124A, T125A, G134D, D167E, V201I, T206S, I208M, T218I, L234I, D256E V281M, S283G
>2931HA| codons 1-288
FLDGIDKAQDEHEKYHSNWRAMASDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFVLKLAGRWPVKVIHTDNGPN
FISAAVKAACWWADIKQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIASDMQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSEIKVVPRRKAKIIRDYGKQMAGDDCMAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, L19P, K20I, E35D, M36I, R41K, H69K, L89M  
>2931HA| codons 1-99
PQITLWQRPLVTVKIGGQPIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V21I, V35T, T39N, E40D, V60I, A98S, K104R, D123K, I135V, K173A, D177E, T200V, Q207K, V245Q, Y271F, A272P, K275R, K277R, Q278E, T286A, E291D, V292I, I293V, P294T, S322A, I326V, G335D, F346H, R356K, M357R, R358G, G359S, V381I, T386L, K390R, A400T, E404D, E432D, V435I, R461K, D471E, Q480Y, L491S, L517I, S519N, K527R, A534S, A554K  
>2931HA| codons 1-560
PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALTEICNDMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKRSVTVLDVGDAYFSVPL
DKKFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPEIVI
YQYMDDLYVGSDLEIGQHRVKIEELRKHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIFPGIRVRELCKLLRGAKALTDIVTLTEEAE
LELAENREILKEPVHGVYYDPAKDLVAEIQKQGQDQWTYQIYQEPHKNLKTGKYAKRGSA
HTNDVKQLTEAVQKIATESIIIWGKLPKFRLPIQKETWETWWTDYWQATWIPEWEFVNTP
PLVKLWYQLEKDPIIGAETFYVDGAANRETKLGKAGYVTDKGRQKVVSLTETTNQKTELY
AIHLALQDSGSEVNIVTDSQYALGIIQAQPDKSESEIVNQIIEQLIRKEKVYLSWVPAHK
GIGGNEQVDKLVSKGIRKVL

References
Author Title Citation
Carr, JK High genetic complexity of HIV-1 in low-prevalence, rural regions of Cameroon. Direct Genbank Submission, 2006