<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
DDJ362 DDJ362 Senegal 1996 HIV1 CRF02_AG PBMC None

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    S24N, V31I, V32I, I72V, L74I, T112V, T124A, T125A, G134N, I135V, K136T, V165I, D167E, V201I, T206S, L234I, D279G S283G
>DDJ362| codons 1-288
FLDGIDKAQEEHEKYHSNWRAMANDFNLPPIIAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVIIVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKVIHTDNGSN
FTSAAVKAACWWANVTQEFGIPYNPQSQGVVESMNKELKKIIGQIREQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIASDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDGCVAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K20I, E35D, M36I, R41K, K43R, F53Y, L63S, H69K, L89M  
>DDJ362| codons 1-99
PQITLWQRPLVTVKIGGQLIEALLDTGADDTVLEDINLPGKWRPKMIGGIGGYIKVRQYD
QISIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, E36A, T39E, K104Q, D123E, I135R, I142V, S162Y, K173L, D177E, V179I, Q207A, R211K, V245Q, T286A, E291D, V292I, I293V, E297K, E312D, D324E, G335D, M357K, G359S, K366R, T369V, A371V, I375V, A376S, E396D, A400T, T403M, W410Y, E432D, R461K, D471E, Q480H, L491A, E492Q, K512R, L517I, S519N, Q524K, I526V, K527E, A534S, A554S  
>DDJ362| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKQSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSRNNETPGVRYQYNVLPQGWKGSPAIFQYSMTKILEPFRLQNPEIII
YQYMDDLYVGSDLEIGQHRTKIEELRAHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVPLTKEAE
LELAENREILKDPVHGVYYDPSKELIAEIQKQGQDQWTYQIYQEPFKNLKTGKYARKRSA
HTNDVRQLVEVVQKVSTESIVIWGKTPKFKLPIQKDTWETWWMEYWQATYIPEWEFVNTP
PLVKLWYQLEKDPIVGAETFYVDGAANRETKLGKAGYVTDKGRQKVVSLTETTNQKTELH
AIHLALQDSGAQVNIVTDSQYALGIIQAQPDRSESEIVNQIIEKLVEKEKVYLSWVPAHK
GIGGNEQVDKLVSSGIRKVL

References
Author Title Citation
Meloni, ST Distinct human immunodeficiency virus type 1 subtype A virus circulating in West Africa: Sub-subtype A3. J Virol, 2004