Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| DDI579 | DDI579 | Senegal | 2001 | HIV1 | A | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| T97A | K14R, A21T, V31I, I72V, L74I, T112V, T124A, T125A, V126M, G134N, D167E, V201I, L234I, V260I | S283G |
| >DDI579| codons 1-288 FLDGIDKAQEEHERYHSNWRTMASDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVIIVAVHVASGYIEAEVIPAETGQEAAYFLLKLAGRWPVKVIHTDNGSN FTSAAMKAACWWANIKQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVIPRRKAKIIRDYGKQMAGDDCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, I13V, K14R, E35D, M36I, R41K, H69K, L89M |
| >DDI579| codons 1-99 PQITLWQRPIVTVRIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| E6K, K11T, V35T, E36A, T39K, K43E, K122E, D123S, I135T, I142V, S162Y, K173S, D177E, V179I, D192N, Q207A, R211K, V245Q, K277R, T286A, E291D, V292I, I293V, P294T, E312D, V317A, G335N, M357K, G359S, A360S, K366R, T369V, A371V, I375V, A376V, K390R, A400T, T403M, W410Y, E432D, V435I, T470M, D471E, Q480H, L491S, K512Q, E514D, L517I, S519N, Q524K, K527E, A534S, A554S |
| >DDI579| codons 1-560 PISPIKTVPVTLKPGMDGPKVKQWPLTEEKIKALTAICKEMEEEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQYSMTKILEPFRSQNPEIII YQYMDDLYVGSNLEIGQHRTKIEELRAHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGAKALTDIVTLTEEAE LELAENREILKDPVHGAYYDPSKDLIAEIQKQGQNQWTYQIYQEPFKNLKTGKYARKRSS HTNDVRQLVEVVQKVVTESIVIWGKTPKFRLPIQKETWETWWMEYWQATYIPEWEFVNTP PLVKLWYQLEKDPIIGAETFYVDGAANRETKLGKAGYVTDRGRQKVVSLMETTNQKTELH AIHLALQDSGSEVNIVTDSQYALGIIQAQPDQSDSEIVNQIIEKLIEKEKVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Meloni, ST | Distinct human immunodeficiency virus type 1 subtype A virus circulating in West Africa: sub-subtype A3. | J Virol, 2004 |