Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 97NE03 | 97NE03 | Niger | 1997 | HIV1 | CRF02_AG | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| K14R, V31I, M50I, S57G, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, D256E | S283G |
| >97NE03| codons 1-288 FLDGIDKAQEEHERYHSNWRAMASDFNLPPIVAKEIVASCDKCQLKGEAIHGQVDCGPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGSN FTSAAVKAACWWANVTQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIASDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSEIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, G17E, K20I, M36I, R41K, H69K, K70R, L89M |
| >97NE03| codons 1-99 PQITLWQRPLVTVRIGEQLIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, V60I, D121H, K122E, I135V, S162A, K166R, K173T, D177E, T200A, Q207E, R211K, V245Q, K277R, T286A, E291D, V292I, I293V, P294T, S322T, G335D, R356K, M357K, G359S, A371V, I375V, K390R, K395R, A400T, T403M, E432D, V435A, S468P, D471E, Q480H, L491S, A508S, K512R, S519N, Q524K, K527E, E529D, A534S, A554N |
| >97NE03| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL HEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTRILEPFRTQNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGAKALTDIVTLTEEAE LELAENREILKEPVHGVYYDPTKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKKRSA HTNDVKQLTEVVQKVATESIVIWGKTPKFRLPIQRETWETWWMEYWQATWIPEWEFVNTP PLVKLWYQLEKDPIAGAETFYVDGAANRETKLGKAGYVTDRGRQKVVPLTETTNQKTELH AIHLALQDSGSEVNIVTDSQYALGIIQSQPDRSESELVNQIIEKLIEKDKVYLSWVPAHK GIGGNEQVDKLVSNGIRKVL |
References
| Author | Title | Citation |
| Mamadou, S | Emergence of complex and diverse CRF02-AG/CRF06-cpx recombinant HIV type 1 strains in Niger, West Africa. | ARHR, 2003 |