Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| EC102 | EC102 | Ecuador | 1990 | HIV1 | B | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| S17N, L28I, P30A, G106A, V201I, L234I, D253E, D256E |
| >EC102| codons 1-288 FLDGIDKAQEEHEKYHNNWRAMASDFNIPAVVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFLLKLAARWPVKTIHTDNGSN FTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQENSEIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12Q, L19V, N37D, K43R, A71T |
| >EC102| codons 1-99 PQITLWQRPLVQIKIGGQVKEALLDTGADDTVLEEMDLPGRWRPKMIGGIGGFIKVRQYD QILIEICGHKTIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K11R, K20R, K122E, D123N, I135T, T200I, I202V, R211K, V245M, A272P, I293V, F346Y, M357V, A376T, T386I, K388H, T403V, V435T, L452S, Q480H, H483N, L491S, K512R, V531T, A554S |
| >EC102| codons 1-560 PISPIETVPVRLKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRIKVEELRQHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPYKNLKTGKYARVRGA HTNDVKQLTEAVQKITTESIVIWGKIPHFKLPIQKETWEAWWVEYWQATWIPEWEFVNTP PLVKLWYQLEKEPITGAETFYVDGAANRETKSGKAGYVTDRGRQKVVSLTDTTNQKTELH AINLALQDSGSEVNIVTDSQYALGIIQAQPDRSESELVSQIIEQLIKKEKTYLAWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Hierholzer, J | Molecular epidemiology of HIV type 1 in Ecuador, Peru, Bolivia, Uruguay, and Argentina. | ARHR, 2002 |