Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| BZ163 | BZ163 | Brazil | 1990 | HIV1 | F | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| G163K | S17N, C56X, I72V, I84L, A91T, L101I, S119T, T124A, T125A, K136Q, V201I, A205S, T206S, T218I, Q221R, L234V, D256E | S283G |
| >BZ163| codons 1-288 FLDGIDKAQEEHEKYHNNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDXSPGI WQLDCTHLEGKVILVAVHVASGYLEAEVIPTETGQETAYFILKLAGRWPVKTIHTDNGTN FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIKQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIISSDIQTKELQKQIIKIRNFRVYYRDSRDPVWKGPAK LLWKGEGAVVIQDNSEIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, E35D, M36I, R41K, R57K, Q61N, L89M |
| >BZ163| codons 1-99 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD NILIEICGHKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, K122E, I135V, S162C, E169D, K173AT, Q174K, I178L, I202V, E203K, Q207E, R211K, V245Q, E248D, A272P, T286A, A288T, E291D, V292I, I293V, E297T, Q334H, R356K, G359S, T377L, Q394L, E399D, A400T, K431T, V435A, L452K, R463K, V466A, D471E, T477A, H483Q, L491S, K512Q, S519N, K527Q, V531I, A534S, V559I |
| >BZ163| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILDPFRAKNPDLVI YQYMDDLYVGSDLEIGQHRTKVKELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKTLTDIVPLTTEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGHGQWTYQIYQEPFKNLKTGKYAKMRSA HTNDVKQLTEAVQKIALESIVIWGKTPKFKLPILKETWDTWWTEYWQATWIPEWEFVNTP PLVKLWYQLETEPIAGAETFYVDGAANRETKKGKAGYVTDRGKQKAVSLTETTNQKAELQ AIQLALQDSGSEVNIVTDSQYALGIIQAQPDQSESELVNQIIEQLIQKEKIYLSWVPAHK GIGGNEQVDKLVSAGIRKIL |
References
| Author | Title | Citation |
| Hierholzer, J | Molecular epidemiology of HIV type 1 in Ecuador, Peru, Bolivia, Uruguay, and Argentina. | ARHR, 2002 |