Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| X1241 | X1241 | Spain | 2002 | HIV1 | F | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | RTI | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| G163K | S17N, I72V, I84L, L101I, S119T, T122S, T124A, T125A, K136Q, D167E, V201I, T218I, L234V, D253E, D256E |
| >X1241| codons 1-288 FLDGIDKAQEEHEKYHNNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYLEAEVIPAETGQETAYFILKLAGRWPVKTIHTDNGTN FSSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIKQVREQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQIIKIQNFRVYYRDSRDPVWKGPAK LLWKGEGAVVIQENSEIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12E, I15V, L19I, E35N, M36I, R41K, R57K, Q61D, I72T, I93L |
| >X1241| codons 1-99 PQITLWQRPLVEIKVGGQIKEALLDTGADDTVLENINLPGKWKPKMIGGIGGFIKVKQYD DILIEICGHKATGTVLVGPTPVNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K219R | V35T, V60I, I135T, Q197K, T200E, Q207E, F214L, A272P, K281R, E297K, K311R, S322L, D324E, R358K, A376T, K390R, Q394L, E399D, A400T, T403S, K431T, V435A, G436E, A446S, L452A, D471E, T477A, Q480H, H483Q, L491S, S519N, K527N, A534S, A554S |
| >X1241| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGKHREKIEELREHLLRWGLTTPDRKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGTKALTEVIPLTKEAE LELAENREILREPVHGVYYDPLKELIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMKGA HTNDVKQLTEAVQKITTESIVIWGKTPKFRLPILKETWDTWWSEYWQATWIPEWEFVNTP PLVKLWYQLETEPIAEAETFYVDGASNRETKAGKAGYVTDRGRQKVVSLTETTNQKAELH AIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLINKEKVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Sierra, M | The analysis of near full-length genome sequences of human immunodeficiency virus type 1 BF intersubtype recombinant viruses from Chile, Venezuela and Spain reveals their relationship to diverse lineages of recombinant viruses related to CRF12_BF. | Infect Genet Evol, 2004 |