Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| JH_Du179 | JH_Du179 | South Africa | 1999 | HIV1 | C | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| D25E, V31I, L45Q, I72V, I84M, F100Y, L101I, T112V, T124S, T125A, K136Q, V201I, T218I, S230N, L234I, A265V, D278A | S283G |
| >JH_Du179| codons 1-288 FLDGIDKAQEEHEKYHSNWRAMASEFNLPPIVAKEIVASCDKCQQKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYMEAEVIPAETGQETAYYILKLAGRWPVKVIHTDNGSN FTSSAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQIIKIQNFRVYYRDNRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGADCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, K14R, I15V, L19I, M36I, N37D, R41K, H69K, L89M, I93L |
| >JH_Du179| codons 1-99 PQITLWQRPLVSIRVGGQIKEALLDTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K32R, V35T, E36A, T39E, E40D, S48T, V60I, K122E, K173A, D177E, T200A, Q207E, R211K, V245N, E248D, A272P, K275Q, K277R, T286A, E291D, V292I, I293V, D324E, Q334D, G335D, R356K, M357R, G359T, A376S, T377L, S379C, K390R, A400I, E404D, E432D, V435L, V458I, T470R, D471E, H483Q, L491S, S519N, Q524E, K530R, A534S, A554S |
| >JH_Du179| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIRALTAICEDMEKEGKITKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPINLPDKDSWTVNDIQKLVGKLNWASQIYPGIQVRQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKELIAEIQKQGDDQWTYQIYQEPFKNLKTGKYAKRRTA HTNDVKQLTEAVQKISLECIVIWGKTPKFRLPIQKETWEIWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKDPILGAETFYVDGAANRETKLGKAGYITDRGRQKVVSLRETTNQKTELQ AIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEELIKKERVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| van Harmelen, J, | Characterization of full-length HIV type 1 subtype C sequences from South Africa. | ARHR, 2001 |