<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
01NGPL0760 01NGPL0760 Nigeria 2001 HIV1 G PBMC None

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    K14R, V31I, M50V, L101I, T112V, T124N, G134N, K136T, I162V, V201I, T206S, I208L, L234I, S255N, D256E S283G
>01NGPL0760| codons 1-288
FLDGIDKAQEEHERYHSNWRAMASDFNLPPIVAKEIVASCDKCQLKGEAVHGQVDCSPGI
WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGSN
FTSNTVKAACWWANITQEFGIPYNPQSQGVVESMNKELKKIVGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIASDLQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNNEIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K20I, E35Q, M36I, N37D, R41K, R57K, C67E, H69K, V82I, L89M  
>01NGPL0760| codons 1-99
PQITLWQRPLVTVKIGGQLIEALLDTGADDTVLEQIDLPGKWKPKMIGGIGGFIKVKQYD
QILIEIEGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, V60I, K122E, D123S, K173T, Q174K, D177E, I178M, T200A, Q207E, V245Q, E248N, A272P, I274V, T286A, E291D, V292I, I293V, P321S, D324E, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, A371V, A376S, T386V, K390R, Q394R, A400V, E413D, Q428R, K431T, V435P, F440Y, R461K, R463K, V467I, S468T, L469I, T470Q, D471E, Q480H, H483Q, L491S, S519N, K530R, A534T, A554S, I556V  
>01NGPL0760| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEMVI
YQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPNKDSWTVNDIQKLVGKLNWASQIYPGVKVKQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDSSKELIAEVQKQGLDQWTYQIYQEPYKNLKTGKYAKRGSA
HTNDVKQLTEVVQKISTESIVIWGKVPKFRLPIRKETWEVWWTEYWQATWIPDWEFVNTP
PLVKLWYRLETEPIPGAETYYVDGAANRETKLGKAGYVTDKGKQKVITIQETTNQKTELH
AIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKERVYLTWVPAHK
GIGGNEQVDKLVSSGVRKVL

References
Author Title Citation
Carr, JK HIV subtype and drug resistance patterns among drug-naive infected persons in Jos, Nigeria. Direct Genbank Submission, 2005