<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
01NGPL0669 01NGPL0669 Nigeria 2001 HIV1 G PBMC None

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    K14R, S24N, L101I, T112V, T124S, T125A, G134S, K136T, V201I, T206S, L234I, D256E S283G
>01NGPL0669| codons 1-288
FLDGIDKAQEEHERYHSNWRAMANDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGSN
FTSSAVKAACWWASITQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIASDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSEIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10I, I13V, K14R, K20I, E35Q, M36I, R41K, R57K, L63P, C67E, H69K, V82I, L89M  
>01NGPL0669| codons 1-99
PQITLWQRPIVTVRIGGQLIEALLDTGADDTVLEQINLPGKWKPKMIGGIGGFIKVKQYD
QIPIEIEGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, K49R, V60I, K122E, D123S, K173T, D177E, I178M, T200A, Q207N, V245Q, E248D, D250E, S251N, E291D, V292I, I293V, K311R, I329V, Q334P, G335D, F346Y, R356K, M357R, R358G, G359S, K366R, T386V, Q394R, A400V, E404D, E413D, Q428R, K431T, V435P, R461K, R463K, V467I, S468T, L469I, T470Q, D471E, Q480H, H483Q, L491S, K512R, S519N, K530R, A534T, A554N  
>01NGPL0669| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTQNPEMVI
YQYMDDLYVGSDLEIGQHRAKIEELRNHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKENWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTDIVPLTEEAE
LELAENREILREPVHGVYYDPSKDLIAEVQKQGPDQWTYQIYQEPYKNLKTGKYAKRGSA
HTNDVRQLTEAVQKIATESIVIWGKVPKFKLPIRKETWEVWWTDYWQATWIPDWEFVNTP
PLVKLWYRLETEPIPGAETFYVDGAANRETKLGKAGYVTDKGKQKVITIQETTNQKTELH
AIQLALQDSGSEVNIVTDSQYALGIIQAQPDRSESELVNQIIEQLIKKERVYLTWVPAHK
GIGGNEQVDKLVSNGIRKVL

References
Author Title Citation
Carr, JK HIV subtype and drug resistance patterns among drug-naive infected persons in Jos, Nigeria. Direct Genbank Submission, 2005