Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| SM_02YE519 | 02YE519 | Yemen | 2002 | HIV1 | B | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| E11D, A23V, S24N, I72V, L101I, T125V, K156R, E157Q, K160Q, K215N, D253E |
| >02YE519| codons 1-288 FLDGIDKAQEDHEKYHSNWRAMVNDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKTIHTDNGSN FTSTVVKAACWWAGIKQEFGIPYNPQSQGVVESMNRQLKQIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQNQITKIQNFRVYYRDSRDPLWKGPAK LLWKGEGAVVIQENSDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| E35D, P39T, R57K, L63P, A71V, I72T, I93L |
| >02YE519| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEDMNLTGRWKPKMIGGIGGFIKVKQYD QIPIEICGHKVTGTVLVGPTPVNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K122E, I135T, S162A, F214L, V245E, A272P, K277R, E297A, L325I, I329L, K390R, A400T, E404D, E449D, E516D, S519N, A554T |
| >02YE519| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTAEAE LELAENREILKEPVHGVYYDPSKDIIAELQKQGQGQWTYQIYQEPFKNLKTGKYARMRGA HTNDVKQLTEAVQKIATESIVIWGKTPKFRLPIQKETWETWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKEPIVGAETFYVDGAANRDTKLGKAGYVTDRGRQKVVSLTDTTNQKTELQ AIHLALQDSGLEVNIVTDSQYALGIIQAQPDKSESDLVNQIIEQLIKKEKVYLAWVPAHK GIGGNEQVDKLVSTGIRKVL |
References
| Author | Title | Citation |
| Saad, MD | HIV type 1 strains common in Europe, Africa, and Asia co-circulate in Yemen. | ARHR, 2005 |