Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CM53658 | CM53658 | Cameroon | 1997 | HIV1 | CRF02_AG | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| K14R, V31I, S57G, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218I, L234I, A265V, R269K | D288N |
| >CM53658| codons 1-288 FLDGIDKAQEEHERYHSNWRAMASDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCGPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGSN FTSAAVKAACWWANVTQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIASDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKVKIIKDYGKQMAGDDCVASRQDEN |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T4S, I13V, K14R, G16E, K20I, E35D, M36I, N37D, H69K, L89M |
| >CM53658| codons 1-99 PQISLWQRPLVTVRIEGQLIEALLDTGADDTVLEDIDLPGRWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E36D, I135V, S162A, K173A, Q174K, D177E, T200A, Q207E, V245Q, E248A, T286A, E291D, V292I, I293V, P294T, S322A, I326V, G335D, P345T, R356K, M357K, G359S, T369A, A371V, I375V, K390R, K395R, T403M, K431R, E432D, R461K, D471E, Q480Y, L491S, K512R, S519N, Q524E, K527Q, E529D, A534S, A554R |
| >CM53658| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTDICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRAKNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPAKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVTLTEEAE LELAENREILKEPVHGVYYDPAKDLVAEIQKQGQDQWTYQIYQETFKNLKTGKYAKKRSA HTNDVKQLAEVVQKVATESIVIWGKTPKFRLPIQRETWEAWWMEYWQATWIPEWEFVNTP PLVKLWYQLERDPIVGAETFYVDGAANRETKLGKAGYVTDKGRQKVVSLTETTNQKTELY AIHLALQDSGSEVNIVTDSQYALGIIQAQPDRSESELVNQIIEELIQKDKVYLSWVPAHK GIGGNEQVDKLVSRGIRKVL |
References
| Author | Title | Citation |
| Carr, JK | The AG recombinant IbNG and novel strains of group M HIV-1 are common in Cameroon. | Virology, 2001 |