Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 99ET17 | 99ET17 | Ethiopia | 1999 | HIV1 | C | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| S17N, V31I, I72V, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, L234I | S283G |
| >99ET17| codons 1-288 FLDGIDKAQEEHEKYHNNWRAMASDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYYILKLAGRWPVKVIHTDNGSN FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, M36I, R41K, L63P, H69K, I93L |
| >99ET17| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QIPIEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, T39E, S48T, K122E, D123S, K173A, D177E, I178L, T200E, Q207N, R211K, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, P294T, S322A, Q334H, G335D, R356K, M357R, G359T, A371V, I375V, K390R, E404D, K431T, V435A, A437V, K454R, V466I, D471E, Q480H, H483Q, L491S, K512N, L517I, S519N, K527N, A534S, A554S |
| >99ET17| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPELVI YQYMDDLYVGSDLEIGQHREKIEELRNHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVTLTEEAE LELAENREILKEPVHGVYYDPAKDLIAEIQKQGHDQWTYQIYQEPFKNLKTGKYAKRRTA HTNDVKQLTEVVQKVATESIVIWGKTPKFRLPIQKETWEAWWTDYWQATWIPEWEFVNTP PLVKLWYQLETEPIAGVETFYVDGAANRETKLGRAGYVTDRGRQKIVSLTETTNQKTELH AIQLALQDSGSEVNIVTDSQYALGIIQAQPDNSESEIVNQIIEQLINKEKVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Harris, ME | A cluster of HIV type 1 subtype C sequences from Ethiopia, observed in full genome analysis, is not sustained in subgenomic regions. | ARHR, 2003 |