Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 99ET14 | 99ET14 | Ethiopia | 1999 | HIV1 | C | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| S24N, D25E, V31I, F100Y, L101I, T112V, T124N, T125A, K136Q, D167E, V201I, T206S, L234I, A265V, D278A | S283G |
| >99ET14| codons 1-288 FLDGIDKAQEEHEKYHSNWRAMANEFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYYILKLAGRWPVKVIHTDNGSN FTSNAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIASDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGADCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M36I, R41K, H69K, L89M, I93L |
| >99ET14| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| E28K, K32E, V35T, E36A, T39E, S48T, K122E, D123G, K173A, D177E, I178L, T200A, Q207E, V245Q, D250E, A272P, K277R, T286A, E291D, V292I, I293V, Q334H, G335D, R356K, G359T, T377M, S379G, T386V, K390R, A400T, E404D, E413D, V435A, A437V, L452I, V466I, D471E, H483Q, L491S, S519N, K527R, K530R, A534S, A554S |
| >99ET14| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTKEKIEALTAICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPELVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGHDQWTYQIYQEPFKNLKTGKYAKMRTA HTNDVKQLTEAVQKIAMEGIVIWGKVPKFRLPIQKETWETWWTDYWQATWIPDWEFVNTP PLVKLWYQLEKEPIAGVETFYVDGAANRETKIGKAGYVTDRGRQKIVSLTETTNQKTELQ AIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIRKERVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Harris, ME | A cluster of HIV type 1 subtype C sequences from Ethiopia, observed in full genome analysis, is not sustained in subgenomic regions. | ARHR, 2003 |