Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A025 | A025 | Argentina | 1999 | HIV1 | B | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| S17N, A23V, S24G, L28I, I72V, T124A, K136N, V165I, T206S, T218S, L234I, D256E | S283G |
| >A025| codons 1-288 FLDGIDKAQEEHEKYHNNWRAMVGDFNIPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSN FTSATVKAACWWAGINQEFGIPYNPQSQGVVESMNKELKKIIGQIRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIVDIIASDIQTKELQKQISKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSEIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V11F, I15V, E35D, M36I, R41K, R57K, Q61N, L89M |
| >A025| codons 1-99 PQITLWQRPLFTIKVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD NILIEICGHKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35I, V60I, K122E, I135M, A272P, K281R, L283I, E297K, L310I, M357T, V365I, K366R, A376T, T386I, A400T, V435I, D460N, R461K, L469I, T470D, H483L, S519N, A554T | D76Y |
| >A025| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICTEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVYFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSMNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLIRGTKALTEVIPLTKEAE LELAENREIIKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARTRGA HTNDIRQLTEAVQKITTESIVIWGKIPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTP PLVKLWYQLEKEPIIGAETFYVDGAANRETKLGKAGYVTNKGRQKVVSIDDTTNQKTELQ AILLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHK GIGGNEQVDKLVSTGIRKVL |
References
| Author | Title | Citation |
| Thomson, MM | Diversity of mosaic structures and common ancestry of human immunodeficiency virus type 1 BF intersubtype recombinant viruses from Argentina revealed by analysis of near full-length genome sequences. | J Gen Virol, 2002 |