<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
01IC_PCI123 01_PCI123 Cote d'Ivoire 2001 HIV1 CRF02_AG PBMC None

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    E11D, K14R, S24N, V31I, K42R, M50I, I72V, I84M, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, I217V, T218S, L234I, D256E S283G
>01_PCI123| codons 1-288
FLDGIDKAQEDHERYHSNWRAMANDFNLPPIVAKEIVASCDRCQLKGEAIHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYMEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGSN
FTSAAVKAACWWANVTQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIASDIQTKELQKQVSKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSEIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K20I, E35D, M36I, R41K, L63P, H69K, K70R, L89M  
>01_PCI123| codons 1-99
PQITLWQRPLVTVKIGGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QIPIEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V21I, K32R, V35T, V60I, K122E, D123N, I135T, E169D, K173E, Q174K, D177E, T200I, Q207E, V245Q, K277R, E291D, V292I, I293V, P294T, F346Y, M357I, R358K, G359S, T377L, K390R, A400T, K431T, E432D, V435G, D471E, Q480Y, H483F, L491S, K512R, L517I, S519N, K527G, E529D, A534S, A554S  
>01_PCI123| codons 1-560
PISPIETVPVKLKPGMDGPKIKQWPLTEEKIRALTEICTEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFREKNPEIVI
YQYMDDLYVGSDLEIGQHRIKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGTKALTDIVTLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPYKNLKTGKYARIKSA
HTNDVKQLTEAVQKIALESIVIWGKTPKFRLPIQKETWETWWTEYWQATWIPEWEFVNTP
PLVKLWYQLETDPIGGAETFYVDGAANRETKLGKAGYVTDRGRQKVVSLTETTNQKTELY
AIFLALQDSGSEVNIVTDSQYALGIIQAQPDRSESEIVNQIIEQLIGKDKVYLSWVPAHK
GIGGNEQVDKLVSSGIRKVL

References
Author Title Citation
Toni, T Presence of CRF09_cpx and complex CRF02_AG/CRF09_cpx recombinant HIV type 1 strains in Cote d'Ivoire, West Africa. ARHR, 2005