Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ML415_2_1997 | 415_2_1997 | Kenya | 1997 | HIV1 | D | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| S17N, I72V, I84M, L101I, T112I, I113V, T124A, T125A, I135V, M154T, V201I, T206S, T218I, L234I, I251L, D256E |
| >415_2_1997| codons 1-288 FLDGIDKAQEEHEKYHNNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYMEAEVIPAETGQETAYFILKLAGRWPVKIVHTDNGSN FTSAAVKAACWWAGVKQEFGIPYNPQSQGVVESTNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIASDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVLQDNSEIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, R41K, I64V, V77I |
| >415_2_1997| codons 1-99 PQITLWQRPLVTVKIGGQLKEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIKVRQYD QILVEICGHKAIGTVLIGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, K49R, V60I, D121H, K122E, Q174R, D177E, I178M, T200S, Q207E, R211K, V245Q, D250E, A272P, K277R, L282C, E291D, I293V, G335D, P345Q, F346Y, R356K, K366R, T377Q, S379C, K390R, A400T, Y427S, V435A, R448K, R461K, L469I, H483N, A485V, V496I, S519N, K527R, A534S, A554N |
| >415_2_1997| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL HEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKRNPEMVI YQYMDDLYVGSDLEIGQHRSKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKCLRGTKALTDVVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEQYKNLKTGKYAKMRGA HTNDVRQLTEAVQKIAQECIVIWGKTPKFRLPIQKETWETWWTEYWQATWIPEWEFVNTP PLVKLWSQLEKEPIAGAETFYVDGAANKETKLGKAGYVTDKGRQKVVSITDTTNQKTELQ AINLVLQDSGLEVNIITDSQYALGIIQAQPDKSESELVNQIIEQLIRKEKVYLSWVPAHK GIGGNEQVDKLVSNGIRKVL |
References
| Author | Title | Citation |
| Fang, G | Long-term survivors in Nairobi: complete HIV-1 RNA sequences and immunogenetic associations. | J Infect Dis, 2004 |