Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ML249_3_1997 | 249_3_1997 | Kenya | 1997 | HIV1 | D | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| S17N, M50I, T112V, I113V, T124A, T125A, V201I, T218I, Q221R, L234I, D256E | D288N |
| >249_3_1997| codons 1-288 FLDGIDKAQEEHEKYHNNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAIHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKVVHTDNGSN FTSAAVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQIIKIRNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSEIKVVPRRKAKIIRDYGKQMAGDDCVASRQDEN |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L19I, M36I, R41K, L63P |
| >249_3_1997| codons 1-99 PQITLWQRPLVTIKIGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QIPIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V179E | P4H, V35T, E40D, K49R, V60I, K122E, A158S, D177E, I178L, T200I, Q207G, R211K, P243Q, V245E, D250E, A272P, K277R, K281R, L282C, L283I, T286A, I293V, G335D, P345Q, F346Y, A355T, R356K, A360T, E370A, T377Q, S379C, K390R, A400T, H483N, A534S, A554N, I556V, V559I |
| >249_3_1997| codons 1-560 PISHIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTDMEKEGKISRIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPSIFQSSMTKILEPFRKQNPELEI YQYMDDLYVGSDLEIGQHRIKIEELRGHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQQIELPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCRCIRGAKALTEVVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEQYKNLKTGKYTKMRGT HTNDVKQLTAAVQKIAQECIVIWGKTPKFRLPIQKETWETWWTEYWQATWIPEWEFVNTP PLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTDRGRQKVVSLTDTTNQKTELQ AINLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVSQIIEQLIKKEKVYLSWVPAHK GIGGNEQVDKLVSNGVRKIL |
References
| Author | Title | Citation |
| Fang, G | Long-term survivors in Nairobi: complete HIV-1 RNA sequences and immunogenetic associations. | J Infect Dis, 2004 |