Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CO9 | CO9 | Tanzania | 2004 | HIV1 | A | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| V31I, I72V, Q95H, G106A, T112V, I113V, T125A, G134N, K136Q, F181L, V201I, L234I | S283G |
| >CO9| codons 1-288 FLDGIDKAQEEHEKYHSNWRAMASDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGHETAYFLLKLAARWPVKVVHTDNGSN FTSTAVKAACWWANIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV LIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I13V, I15V, K20R, M36I, R41K, L63T, C67Y, H69K, L89M, I93L |
| >CO9| codons 1-99 PQITLWQRPLVSVKVGGQLREALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QITIEIYGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, V60I, K173A, Q174K, D177E, T200A, Q207E, V245Q, T286A, V292T, I293V, P294A, E312N, K323R, G335D, M357K, G359S, T369A, A371V, I375V, A376G, T377M, T386S, A400T, T403M, E404D, W410Y, E432D, D471E, Q480H, L491S, L503I, K512R, L517I, S519N, Q524K, K527G, E529D, A534S, A554S |
| >CO9| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTETVALTEEAE LELAENREILKNPVHGVYYDPSRDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYARKRSA HTNDVKQLAEVVQKVGMESIVIWGKSPKFKLPIQKETWETWWMDYWQATYIPEWEFVNTP PLVKLWYQLEKDPIVGAETFYVDGAANRETKLGKAGYVTDRGRQKVVSLTETTNQKTELH AIHLALQDSGSEVNIVTDSQYAIGIIQAQPDRSESEIVNQIIEKLIGKDKVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Arroyo, MA | HIV-1 diversity and prevalence differ between urban and rural areas in the Mbeya region of Tanzania. | AIDS, 2005 |