Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CO3305 | CO3305 | Tanzania | 2004 | HIV1 | C | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| E11D, K14R, S24N, D25E, V31I, S39C, S57G, I72V, L101I, T112V, T124A, T125A, K136Q, D167E, V201I, K215N, T218I, L234I, D278A | S283G |
| >CO3305| codons 1-288 FLDGIDKAQEDHERYHSNWRAMANEFNLPPIVAKEIVACCDKCQLKGEAMHGQVDCGPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGSN FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQNQIIKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGADCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, L19V, E35D, M36I, R41K, L63A, H69K, T74S, L89M, I93L |
| >CO3305| codons 1-99 PQITLWQRPLVTIKVGGQVKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QIAIEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K20R, V35T, E36A, T39E, S48T, V60I, K122E, D123S, I142L, K173T, Q174K, T200A, Q207A, R211K, P243H, V245Q, K277R, E291D, V292I, I293V, Q334N, G335D, R356K, G359T, T377Q, K390R, A400T, E404D, E413D, E449D, T450R, L452I, V466I, V467I, T470N, D471E, H483Q, L491P, S519N, K527N, K530R, A534S, A554S |
| >CO3305| codons 1-560 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSINNETPGLRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPDIVI YQYMDDLYVGSDLEIGQHRAKIEELRAHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQHIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGTKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGNDQWTYQIYQEPFKNLKTGKYAKMRTA HTNDVKQLTEAVQKIAQESIVIWGKTPKFRLPIQKETWETWWTDYWQATWIPDWEFVNTP PLVKLWYQLEKEPIVGAETFYVDGAANRDRKIGKAGYVTDRGRQKIISLNETTNQKTELQ AIQLALQDSGPEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLINKERVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Arroyo, MA | HIV-1 diversity and prevalence differ between urban and rural areas in the Mbeya region of Tanzania. | AIDS, 2005 |