Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| BB_96TH_NP1046 | 96TH_1046 | Thailand | 1996 | HIV1 | CRF01_AE | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| K14R, A21T, V31I, V32I, M50I, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, T206S, L234I | S283G |
| >96TH_1046| codons 1-288 FLDGIDKAQEEHERYHSNWRTMASDFNLPPIIAKEIVASCDKCQLKGEAIHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKVIHTDNGSN FTSAAVKAACWWANVRQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIASDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, E35D, M36I, R41K, H69K, K70R, L89M |
| >96TH_1046| codons 1-99 PQITLWQRPLVTVKIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V108I | E6D, K11T, V35T, T39K, K43E, K102R, K104R, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245E, A272P, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, I341L, M357K, G359S, K366R, A371V, V381I, T386I, K390R, K395R, A400T, E432D, D471E, Q480H, H483Y, L491S, K512R, L517V, Q524E, A534S, A554S |
| >96TH_1046| codons 1-560 PISPIDTVPVTLKPGMDGPKVKQWPLTEEKIKALTEICKEMEEEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKRKRSVTILDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPEMVI YQYMDDLYVGSDLEIGQHRIKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDRWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTEEAE LELAENREILKTPVHGVYYDPSKDLVAEVQKQGQDQWTYQLYQEPFKNLKTGKYARKRSA HTNDVRQLTEVVQKIATESIIIWGKIPKFRLPIQRETWETWWTEYWQATWIPEWEFVNTP PLVKLWYQLEKDPIVGAETFYVDGAANRETKLGKAGYVTDRGRQKVVSLTETTNQKTELH AIYLALQDSGSEVNIVTDSQYALGIIQAQPDRSESEVVSQIIEELIKKEKVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Brown, BK | Biologic and genetic characterization of a panel of 60 human immunodeficiency virus type 1 isolates, representing clades A, B, C, D, CRF01_AE, and CRF02_AG, for the development and assessment of candidate vaccines. | J Virol, 2005 |