Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| BB_93UG_065 | 93UG_065 | Uganda | 1993 | HIV1 | D | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| S17N, M50L, I72V, T112V, I113V, T124A, T125A, V201I, L234I, D256E |
| >93UG_065| codons 1-288 FLDGIDKAQEEHEKYHNNWRAMASDFNLPPVVAKEIVASCDKCQLKGEALHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKVVHTDNGSN FTSAAVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSEIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M36I, R41K, K70N |
| >93UG_065| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGHNAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K22R, V35T, E36K, K49R, V60I, K82R, D121Y, K122E, D123E, S162C, T165I, D177E, I178M, T200I, Q207G, R211K, V245K, D250E, A272P, I274V, K277R, L282C, T286A, I293V, P294T, E312A, G335N, P345Q, F346Y, R356K, T377Q, S379C, K390R, A400T, E413D, V435I, V458I, H483N, L491S, Q524K, K527E, A534S, A554N, V559I |
| >93UG_065| codons 1-560 PISPIETVPVKLKPGMDGPKVRQWPLTEEKIKALTKICTEMEKEGKISRIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNRRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL YEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMIKILEPFRKQNPEMVI YQYMDDLYVGSDLEIGQHRIKIEELRGHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIKLPEKESWTVNDIQKLVGKLNWASQIYPGVKVRQLCKCLRGAKALTEVVTLTEEAE LELAENREILKAPVHGVYYDPSKDLIAEIQKQGQNQWTYQIYQEQYKNLKTGKYAKMRGA HTNDVKQLTEAVQKIAQECIVIWGKTPKFRLPIQKETWETWWTEYWQATWIPDWEFVNTP PLVKLWYQLEKEPIIGAETFYVDGAANRETKLGKAGYITDRGRQKVVSLTDTTNQKTELQ AINLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVSQIIEKLIEKEKVYLSWVPAHK GIGGNEQVDKLVSNGIRKIL |
References
| Author | Title | Citation |
| Brown, BK | Biologic and genetic characterization of a panel of 60 human immunodeficiency virus type 1 isolates, representing clades A, B, C, D, CRF01_AE, and CRF02_AG, for the development and assessment of candidate vaccines. | J Virol, 2005 |