Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| KNH1239 | KNH1239 | Kenya | 2000 | HIV1 | A | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| S24Q, I72V, T112V, S119P, T122I, T124A, K136Q, K173R, V201I, K211R, E212A, K215R, Q216N, K219Q, L234I | S283G |
| >KNH1239| codons 1-288 FLDGIDKAQEEHEKYHSNWRAMAQDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKVIHTDNGPN FISATVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLRTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTRALQRNITQIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, G16E, E35D, M36I, R41K, L63A, H69K, K70R, L89M, T91V |
| >KNH1239| codons 1-99 PQITLWQRPLVTVKIEGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QIAIEICGKRAIGTVLVGPTPVNIIGRNMLVQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, K49R, K102R, D121H, K122E, D123E, I142V, D177E, Q207E, R211K, V245Q, K281R, E291D, V292I, I293V, E297K, A304E, E312N, G335D, R356K, M357K, G359S, A360T, T377M, K390R, K431R, V435A, A446S, V466I, D471E, K476R, Q480H, H483Y, K512R, E514D, S519N, Q524K, K527E, K530R, A534S, A554S |
| >KNH1239| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKRKKSVTVLDVGDAYFSVPL HEEFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI YQYMDDLYVGSDLEIGQHRTKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCRLLRGTKALTDIVPLTKEAE LELEENREILKNPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKKRST HTNDVKQLTEAVQKIAMESIVIWGKTPKFRLPIQKETWEAWWTEYWQATWIPEWEFVNTP PLVKLWYQLEREPIAGAETFYVDGASNRETKLGKAGYVTDRGRQKIVSLTETTNQRTELH AIYLALQDSGLEVNIVTDSQYALGIIQAQPDRSDSELVNQIIEKLIEKERVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Visawapoka, U | Circulating and unique recombinant forms of HIV Type 1 containing subsubtype A2. | ARHR, 2006 |