Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 97TZ04 | 97TZ04 | Tanzania | 1997 | HIV1 | C | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| S17N, L28I, I72V, I84M, T112V, I113V, T124N, T125A, K136Q, V201I, T218I, L234I, A265V, R269K, D278A | S283G |
| >97TZ04| codons 1-288 FLDGIDKAQEEHEKYHNNWRAMASDFNIPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYMEAEVIPAETGQETAYFLLKLAGRWPVKVVHTDNGSN FTSNAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKVKIIKDYGKQMAGADCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, M36I, R41K, L63P, H69K, I93L |
| >97TZ04| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QIPIEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E36A, T39E, S48T, K122E, I135T, K154E, S162C, K173A, Q174R, D177E, Q197K, T200A, I202V, Q207E, P243T, V245Q, A272P, K275R, T286A, E291D, V292I, I293V, P294T, Q334H, G335D, R356K, G359T, T377M, P387S, K390R, A400T, E404D, E413D, L452V, V466I, S468T, T470A, D471E, H483Q, L491S, S519N, A534S, A554S | R172G |
| >97TZ04| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWEGSPAIFQCSMTKILEPFGARNPEIVI YQYMDDLYVGSDLEIGKHRAKVEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQTIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIRVKQLCKLLRGAKALTDIVTLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGHDQWTYQIYQEPFKNLKTGKYAKMRTA HTNDVKQLTEAVQKIAMESIVIWGKTSKFRLPIQKETWETWWTDYWQATWIPDWEFVNTP PLVKLWYQLEKEPIVGAETFYVDGAANRETKVGKAGYVTDRGRQKIVTLAETTNQKTELQ AIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Hoelscher, M | High proportion of unrelated HIV-1 intersubtype recombinants in the Mbeya region of southwest Tanzania. | AIDS, 2001 |