Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 97TZ02 | 97TZ02 | Tanzania | 1997 | HIV1 | A | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| K14R, V31I, I72V, L101I, T112V, I113V, T124A, T125A, I135V, K136Q, V201I, A205S, T218I, L234I, A265V | S283G |
| >97TZ02| codons 1-288 FLDGIDKAQEEHERYHSNWRAMASDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVVHTDNGSN FTSAAVKAACWWAGVQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIISTDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, E35D, M36I, N37D, R41K, R57K, D60E, I62V, H69K, L89M |
| >97TZ02| codons 1-99 PQITLWQRPLVTVRIGGQLKEALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFIKVKQYE QVLIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, V60I, K122E, I135T, K173L, Q174K, D177E, V179I, Q207A, R211S, V245E, D250E, K281R, T286A, E291A, V292I, I293V, P294T, E312N, G335D, M357K, G359S, T369A, A371V, I375V, A376V, A400T, T403M, E404D, E413D, E432D, S468P, D471E, Q480H, H483Y, L491S, Q507H, K512R, S519N, Q524K, K527E, E529D, A534S, A554S |
| >97TZ02| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRLKNPEIII YQYMDDLYVGSDLEIGQHRTKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCRLLRGAKALTAIVTLTEEAE LELAENREILKNPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYARKRSA HTNDVKQLAEVVQKVVTESIVIWGKTPKFKLPIQKETWETWWMDYWQATWIPDWEFVNTP PLVKLWYQLEKDPIVGAETFYVDGAANRETKLGKAGYVTDRGRQKVVPLTETTNQKTELH AIYLALQDSGSEVNIVTDSQYALGIIHAQPDRSESELVNQIIEKLIEKDKVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Hoelscher, M | High proportion of unrelated HIV-1 intersubtype recombinants in the Mbeya region of southwest Tanzania. | AIDS, 2001 |