Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 00BW2036 | 00BW2036 | Botswana | 2000 | HIV1 | C | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| D25E, V31I, M50I, L74I, V77A, L101I, T112V, T124A, T125A, K136Q, V201I, L234I, A265V, R269K, D278A | S283G |
| >00BW2036| codons 1-288 FLDGIDKAQEEHEKYHSNWRAMASEFNLPPIVAKEIVASCDKCQLKGEAIHGQVDCSPGI WQLDCTHLEGKIIIVAAHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGSN FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKVKIIKDYGKQMAGADCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, N37S, R41K, L63P, H69K, V77I, L89M, I93L |
| >00BW2036| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEMSLPGKWKPKMIGGIGGFIKVRQYD QIPIEICGKKAIGTVLIGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K11R, V35T, E36A, T39E, S48T, K122E, D123N, K173A, Q174K, D177E, I178L, T200A, K201R, Q207K, V245K, D250E, A272P, T286A, E291D, V292I, I293V, L301V, K311R, E312G, I326V, Q334H, G335D, Y342F, R356K, G359T, T377M, K390R, A400T, E404D, V435I, V466I, V467I, D471E, H483Q, L491S, S519N, K530R, A534S, A554R | D256G |
| >00BW2036| codons 1-560 PISPIETVPVRLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPELVI YQYMDDLYVGSDLEIGQHRARIEELRKHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIKLPEKESWTVNGIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTEEAE VELAENREILRGPVHGVYYDPSKDLVAEIQKQGHDQWTYQIFQEPFKNLKTGKYAKMRTA HTNDVKQLTEAVQKIAMESIVIWGKTPKFRLPIQKETWETWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKEPIIGAETFYVDGAANRETKLGKAGYVTDRGRQKIISLTETTNQKTELQ AIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKERVYLSWVPAHK GIGGNEQVDKLVSRGIRKVL |
References
| Author | Title | Citation |
| Novitsky, V | Human immunodeficiency virus type 1 subtype C molecular phylogeny: consensus sequence for an AIDS vaccine design? | J Virol, 2002 |