Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 99BW3932 | 99BW3932 | Botswana | 1999 | HIV1 | C | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| Q9R, D25E, V31I, M50T, I72V, L101I, T112V, T124A, T125A, K136Q, V201I, K211R, T218I, K219Q, L234I, R269K, D278A |
| >99BW3932| codons 1-288 FLDGIDKAREEHEKYHSNWRAMASEFNLPPIVAKEIVASCDKCQLKGEATHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGSN FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTRELQKQIIQIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIKDYGKQMAGADCVASRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| F53L | T12P, I15V, L19I, M36I, R41K, I62V, L63V, G68E, H69K, A71T, I93L |
| >99BW3932| codons 1-99 PQITLWQRPLVPIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGLIKVRQYD QVVIEICEKKTIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, T39K, S48E, L100X, K122E, E138A, E169K, K173E, D177E, I178M, R199T, T200A, Q207D, R211G, V245Q, D250E, A272P, K277R, T286A, E291D, V292I, I293V, I309L, A327T, Q334H, G335D, R356K, G359S, T362P, Q373H, T377M, K390R, A400T, E404D, V435G, A437V, L452V, R461K, V467I, S468T, L469I, T470N, D471E, H483Y, L491S, S519N, K530R, A534S, A554S |
| >99BW3932| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICKEMEKEGKIEKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGFKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNATPGIRYQYNVLPQGWKGSPAIFQSSMTKILKPFREQNPEMVI YQYMDDLYVGSDLEIGQHTAKIEELRDHLLGWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAE LELAENRELLKEPVHGVYYDPSKDLITEIQKQGHDQWTYQIYQEPFKNLKTGKYAKMRSA HPNDVKQLTEAVHKIAMESIVIWGKTPKFRLPIQKETWETWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKEPIGGVETFYVDGAANRETKVGKAGYVTDKGRQKVITINETTNQKTELQ AIYLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKERVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Novitsky, V | Human immunodeficiency virus type 1 subtype C molecular phylogeny: consensus sequence for an AIDS vaccine design? | J Virol, 2002 |