Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 98BWMC13 | 98BWMC13 | Botswana | 1998 | HIV1 | C | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| E10D, E11D, K14R, S24N, D25E, V31I, M50I, F100Y, L101I, T112I, T124A, T125A, K136Q, V201I, K211R, T218I, S230N, L234I, D256E, A265V, D278A | S283G |
| >98BWMC13| codons 1-288 FLDGIDKAQDDHERYHSNWRAMANEFNLPPIVAKEIVASCDKCQLKGEAIHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYYILKLAGRWPVKIIHTDNGSN FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTRELQKQIIKIQNFRVYYRDNRDPIWKGPAK LLWKGEGAVVIQDNSEIKVVPRRKVKIIRDYGKQMAGADCVAGRQDED |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E36A, T39E, S48T, K122E, D123G, I135V, S162C, K173A, D177E, Q197K, T200A, Q207R, V245Q, D250E, A272P, T286A, E291D, V292I, I293V, I326V, Q334L, G335D, R356K, M357R, R358K, G359T, T377L, T386I, K390R, A400T, E404D, V435L, A437V, V458I, D471E, H483Q, L491P, S519N, K530R, A534S, A554S |
| >98BWMC13| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRAQNPEIVI YQYMDDLYVGSDLEIGKHRAKIEELRRHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLVAEIQKQGLDQWTYQIYQEPFKNLKTGKYAKRKTA HTNDVKQLTEAVQKIALESIVIWGKIPKFRLPIQKETWETWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKEPILGVETFYVDGAANRETKLGKAGYITDRGRQKVVSLTETTNQKTELQ AIQLALQDSGPEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKERVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Novitsky, V | Human immunodeficiency virus type 1 subtype C molecular phylogeny: consensus sequence for an AIDS vaccine design? | J Virol, 2002 |