Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 96BWMO1 | 96BWMO1 | Botswana | 1996 | HIV1 | C | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| K14R, D25E, V31I, M50I, I84M, T112I, T124A, T125A, K136Q, V201I, K211R, T218I, S230N, L234I, D256E, D278A | S283G |
| >96BWMO1| codons 1-288 FLDGIDKAQEEHERYHSNWRAMASEFNLPPIVAKEIVASCDKCQLKGEAIHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYMEAEVIPAETGQETAYFLLKLAGRWPVKIIHTDNGSN FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTRELQKQIIKIQNFRVYYRDNRDPIWKGPAK LLWKGEGAVVIQDNSEIKVVPRRKAKIIRDYGKQMAGADCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, M36V, R41K, L63P, H69K, K70R, L89M, I93L |
| >96BWMO1| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEVNLPGKWKPKMIGGIGGFIKVRQYD QIPIEICGKRAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E36A, T39E, S48T, K122E, D123G, P170L, K173A, Q174K, D177E, T200A, Q207E, R211K, K238Q, V245Q, D250E, A272P, K277R, T286A, E291D, V292I, I293V, E297D, K311R, Q334H, G335D, R356K, M357R, G359T, T377L, I380T, T386I, K390R, E399D, A400T, E404D, V435L, L452M, S468P, D471E, H483Q, L491S, G504K, S519N, E529D, K530R, A534S, A554S |
| >96BWMO1| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILELFRAKNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDQWT VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTDEAE LELAENREILREPVHGVYYDPSKDLIAEIQKQGHDQWTYQIYQEPFKNLKTGKYAKRRTA HTNDVKQLTEAVQKIALESTVIWGKIPKFRLPIQKETWDTWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKEPILGAETFYVDGAANRETKMGKAGYVTDRGRQKVVPLTETTNQKTELQ AIQLALQDSGSEVNIVTDSQYALKIIQAQPDKSESELVNQIIEQLIKKDRVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Novitsky, V | Human immunodeficiency virus type 1 subtype C molecular phylogeny: consensus sequence for an AIDS vaccine design? | J Virol, 2002 |