Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 00THOUR746I | 00_746I | Thailand | 2000 | HIV1 | CRF01_AE | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| K14R, A21T, A23V, S39N, I72V, T112V, T124A, T125A, K127R, G134N, I135V, K136R, D167E, V201I, L234I | S283G |
| >00_746I| codons 1-288 FLDGIDKAQEEHERYHSNWRTMVSDFNLPPVVAKEIVANCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKVIHTDNGSN FTSAAVRAACWWANVRQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12P, I13V, G16A, E35D, M36I, R41K, D60E, H69K, L89M |
| >00_746I| codons 1-99 PQITLWQRPLVPVKIAGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYE QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| E6D, K11T, V35T, T39K, K43E, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245E, E291D, V292I, I293V, K311R, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, E432D, N447S, D471E, Q480H, L491S, K512R, L517V, Q524E, A534S, A554T |
| >00_746I| codons 1-560 PISPIDTVPVTLKPGMDGPKVKQWPLTEEKIKALTEICKEMEEEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPEMVI YQYMDDLYVGSDLEIGQHRIKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDRWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTDIVPLTEEAE LELAENREILRTPVHGVYYDPSKDLVAEVQKQGQDQWTYQIYQEPFKNLKTGKYARKRSA HTNDVRQLTEVVQKIATESIVIWGKTPKFRLPIQRETWETWWTEYWQATWIPEWEFVNTP PLVKLWYQLEKDPIVGAETFYVDGAASRETKLGKAGYVTDRGRQKVVSLTETTNQKTELH AIHLALQDSGSEVNIVTDSQYALGIIQAQPDRSESEVVSQIIEELIKKEKVYLSWVPAHK GIGGNEQVDKLVSTGIRKVL |
References
| Author | Title | Citation |
| Tovanabutra, S | The changing molecular epidemiology of HIV type 1 among northern Thai drug users, 1999 to 2002. | ARHR, 2004 |