<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
01TZA280 01TZA280 Tanzania 2001 HIV1 D PBMC None

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    E11D, K14R, P30S, S39C, I72V, L101I, T112V, T124A, K156R, V201I, T206S, I208L, K211T, L234I, N254H, M275V  
>01TZA280| codons 1-288
FLDGIDKAQEDHERYHSNWRAMASDFNLPSVVAKEIVACCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGSN
FTSATVKAACWWAGIKQEFGIPYNPQSQGVVESMNRELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIASDLQTTELQKQITKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDHSDIKVVPRRKAKIIRDYGKQVAGDDCVASRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    N37S, R41K, H69Q  
>01TZA280| codons 1-99
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGQKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        E6A, V35T, K49R, V60I, I135T, D177E, Q207D, R211K, V245K, D250E, A272S, T286A, E297K, K311R, P313T, V317A, G333E, R356K, A360T, T377L, S379G, T386I, K390R, A400T, V435I, K451R, R461K, H483N, V496I, A554S  
>01TZA280| codons 1-560
PISPIATVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI
YQYMDDLYVGSDLEIGQHRTKIEELRDHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIKLPEKESWTVNDIQKLVGKLNWASQIYSGIKVKQLCKLLRGAKALTEVIPLTKEAE
LELAENREILRETVHGAYYDPSKDLIAEIQKQEQGQWTYQIYQEPFKNLKTGKYAKMRGT
HTNDVKQLTEAVQKIALEGIVIWGKIPKFRLPIQKETWETWWTEYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIIGAETFYVDGAANRETRLGKAGYVTDKGRQKVVSLTDTTNQKTELQ
AINLALQDSGLEVNIITDSQYALGIIQAQPDKSESELVSQIIEQLIKKEKVYLAWVPAHK
GIGGNEQVDKLVSSGIRKVL

References
Author Title Citation
Arroyo, MA HIV type 1 subtypes among blood donors in the Mbeya region of southwest Tanzania. ARHR, 2004