<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
01TZA195 01TZA195 Tanzania 2001 HIV1 A PBMC None

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    K14R, A21T, S24N, V31I, S39N, M50I, I60M, I72V, T112V, I113V, T124A, T125A, V126F, I135V, K136Q, F139Y, V165I, D167E, V201I, Q216N, T218I, L234I, I268L, D270H S283G
>01TZA195| codons 1-288
FLDGIDKAQEEHERYHSNWRTMANDFNLPPIVAKEIVANCDKCQLKGEAIHGQVDCSPGM
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKVVHTDNGSN
FTSAAFKAACWWAGVQQEYGIPYNPQSQGVVESMNKELKKIIGQIREQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKNIIKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKILRHYGKQMAGDDCVAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, Q18L, E35D, M36I, R41K, K45R, R57K, L63S, H69K, L89M  
>01TZA195| codons 1-99
PQITLWQRPLVTVRIGGLLKEALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVKQYD
QISIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, T39I, V60I, K122E, D123N, I135T, K173L, Q174K, D177E, V179I, Q207A, R211S, V245I, D250E, K275S, T286A, E291D, I293V, P294T, E312D, D324E, G335D, M357K, G359S, A360T, A371V, I375V, A376V, A400T, E404D, E432D, V435A, V466I, D471E, Q480H, L491S, K512R, S519N, Q524K, K527G, E529D, A534S, A554S  
>01TZA195| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICIEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRLKNPEIII
YQYMDDLYVGSDLEIGQHRTKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIILPEKESWTVNDIQKLVGKLNWASQIYAGISVKQLCKLLRGAKALTDVVTLTEEAE
LELAENREILKDPVHGVYYDPSKELIAEIQKQGQDQWTYQIYQEPFKNLKTGKYARKRST
HTNDVKQLTEVVQKVVTESIVIWGKTPKFKLPIQKETWETWWTDYWQATWIPEWEFVNTP
PLVKLWYQLEKDPIAGAETFYVDGAANRETKLGKAGYVTDRGRQKIVSLTETTNQKTELH
AIHLALQDSGSEVNIVTDSQYALGIIQAQPDRSESELVNQIIEKLIGKDKVYLSWVPAHK
GIGGNEQVDKLVSSGIRKVL

References
Author Title Citation
Arroyo, MA HIV type 1 subtypes among blood donors in the Mbeya region of southwest Tanzania. ARHR, 2004