<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
99TCDMN012 99TCDMN012 Chad 1999 HIV1 D PBMC None

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    D6S, K7Q, E13D, T112V, I113V, T124A, T125A, V201I, K211R, T218I, L234I, D253E, A265V, R269K, D279G  
>99TCDMN012| codons 1-288
FLDGISQAQEEHDKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKVVHTDNGSN
FTSAAVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDIQTRELQKQIIKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQENSDIKVVPRRKVKIIKDYGKQMAGDGCVASRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    E35D, M36I, N37D, R41K, D60E, I62V, I64V  
>99TCDMN012| codons 1-99
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFIKVRQYE
QVLVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V21I, V35T, K49R, V60I, K122E, D123N, S162C, D177E, I178L, E204Q, Q207E, P243S, V245I, E248H, K249Q, D250E, A272P, Q278H, K281R, T286A, E297K, K311R, I329V, G335S, T338S, Y339W, T377L, K390R, T403M, V435I, S468P, L469F, H483N, L491P, L517V, Q524L, A554S, K558*  
>99TCDMN012| codons 1-560
PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPELVI
YQYMDDLYVGSDLEIGQHRTKIEQLREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQSIILPHQESWTVNDIQKLVGKLNWASQIYPGIKVKHLCRLLRGAKALTEVIPLTKEAE
LELAENREILREPVHGVYYDPSKDLIAEVQKQGQSQWSWQIYQEPFKNLKTGKYARMRGA
HTNDVKQLTEAVQKIALESIVIWGKTPKFRLPIQKETWEAWWMEYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIIGAETFYVDGAANRETKLGKAGYVTDRGRQKVVPFTDTTNQKTELQ
AINLALQDSGPEVNIVTDSQYALGIIQAQPDKSESEVVSQIIELLIKKEKVYLAWVPAHK
GIGGNEQVDKLVSSGIR*VL

References
Author Title Citation
Vidal, N High genetic diversity of HIV-1 strains in Chad, West Central Africa. JAIDS, 2003