Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Cu87 | Cu87 | Cuba | 1999 | HIV1 | G | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | Unknown | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| E11D, K14R, S17T, A23V, V31I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, Y227F, L234I, S255N, D256E | S283G |
| >Cu87| codons 1-288 FLDGIDKAQEDHERYHTNWRAMVSDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGSN FTSAAVKAACWWANVTQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIASDIQTKELQKQITKIQNFRVYFRDSRDPIWKGPAK LLWKGEGAVVIQDNNEIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, K20I, E35D, M36I, R41K, H69K, V82I, L89M |
| >Cu87| codons 1-99 PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V21I, V35T, V60I, K122E, I135V, S162C, K173T, Q174K, D177E, T200A, E203D, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, I329V, G333E, G335D, F346Y, R356K, M357R, R358G, G359S, K366R, A371V, K390R, Q394R, E399D, A400V, T403A, E404D, E413D, Q428R, K431T, V435P, F440Y, R461K, R463K, V466I, V467I, S468T, D471E, H483Q, L491P, K512R, L517I, S519N, A534S, A554S |
| >Cu87| codons 1-560 PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRTKNPEIVI YQYMDDLYVGSDLEIGQHRAKIDELRQHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTAEAE LELAENREILKEPVHGVYYDPSKDLIAEVQKQEQDQWTYQIYQEPYKNLKTGKYAKRGSA HTNDVRQLTEVVQKIATESIVIWGKTPKFRLPIRKETWDVWWADYWQATWIPDWEFVNTP PLVKLWYRLETEPIPGAETYYVDGAANRETKLGKAGYVTDKGKQKIITLTETTNQKTELQ AIQLALQDSGPEVNIVTDSQYALGIIQAQPDRSESEIVNQIIEQLIKKEKVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Sierra, M | Identification of 3 phylogenetically related HIV-1 BG intersubtype circulating recombinant forms in Cuba. | JAIDS, 2007 |