Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Cu74 | Cu74 | Cuba | 1999 | HIV1 | G | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | Unknown | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| K14R, V31I, V32I, L101I, T112V, T124A, T125A, G134N, K136T, V201I, T206S, Y227F, L234I, S255N, D256E, D279A | S283G |
| >Cu74| codons 1-288 FLDGIDKAQEEHERYHSNWRAMASDFNLPPIIAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGSN FTSAAVKAACWWANITQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIASDIQTKELQKQITKIQNFRVYFRDSRDPIWKGPAK LLWKGEGAVVIQDNNEIKVVPRRKAKIIRDYGKQMAGDACVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, K20I, E35D, M36I, R41K, H69K, V82I, L89M |
| >Cu74| codons 1-99 PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V179E | V21I, V35T, E36D, T39A, E40D, V60I, I135T, D177E, T200A, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, D324E, L325I, I329V, Q334N, G335D, F346Y, R356K, M357R, R358G, G359S, T369V, A371V, A376S, Q394R, A400V, E404D, E413D, Q428R, K431T, V435L, F440Y, R461N, R463K, V467I, S468T, H483Q, L491S, K512R, S519N, A534S, A554T | I50F |
| >Cu74| codons 1-560 PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALTDICADMEKEGKISKFGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIEI YQYMDDLYVGSDLEIGQHRAKIEELRQHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKEIIAEVQKQGNDQWTYQIYQEPYKNLKTGKYAKRGSA HTNDVKQLVEVVQKISTESIVIWGKTPKFKLPIRKETWEVWWTDYWQATWIPDWEFVNTP PLVKLWYRLETEPILGAETYYVDGAANRETKLGKAGYVTDNGKQKVITLTDTTNQKTELQ AIQLALQDSGSEVNIVTDSQYALGIIQAQPDRSESELVNQIIEQLIKKEKVYLSWVPAHK GIGGNEQVDKLVSTGIRKVL |
References
| Author | Title | Citation |
| Sierra, M | Identification of 3 phylogenetically related HIV-1 BG intersubtype circulating recombinant forms in Cuba. | JAIDS, 2007 |