Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| R77 | R77 | Cuba | 1999 | HIV1 | G | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | Unknown | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| E11D, K14R, S24N, V31I, T112V, S119P, T122I, T124A, T125A, G134N, K136T, V201I, T206S, L234I, S255N, D256E | S283G |
| >R77| codons 1-288 FLDGIDKAQEDHERYHSNWRAMANDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKVIHTDNGPN FISAAVKAACWWANITQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIASDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNNEIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, K20I, E35D, M36I, R41K, H69K, V82I, L89M, T96P |
| >R77| codons 1-99 PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPINIIGRNMLTQIGCPLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| S3R, P14S, S48A, K122E, D123N, I135T, S162C, D177E, R211K, F214L, V245Q, E248D, A272P, K277R, I293V, E297T, I326T, M357I, R358K, T377Q, K390R, T403M, T450N, R463K, S468P, H483L, A554S | K30E |
| >R77| codons 2-560 IRPIETVPVKLKSGMDGPKVKQWPLTEEEIKALVEICTEMEKEGKIAKIGPENPYNTPVF AIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLD ENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPEIVIY QYMDDLYVGSDLEIGQHRTKIEELRQHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWTV QPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVVPLTTEAEL ELAENREILKEPVHGVYYDPSKDLTAEIQKQGQGQWTYQIYQEPFKNLKTGKYARIKGAH TNDVKQLTEAVQKIAQESIVIWGKTPKFRLPIQKETWEAWWMEYWQATWIPEWEFVNTPP LVKLWYQLEKEPIVGAETFYVDGAANRENKLGKAGYVTDRGKQKVVPLTDTTNQKTELQA ILLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVSQIIEQLIKKEKVYLAWVPAHKG IGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Sierra, M | Identification of 3 phylogenetically related HIV-1 BG intersubtype circulating recombinant forms in Cuba. | JAIDS, 2007 |