Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 99TH_R1149 | 99_R1149 | Thailand | 1999 | HIV1 | CRF01_AE | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| K14R, A21T, I72V, T112V, T124A, T125A, G134N, I135V, K136R, K160R, D167E, V201I, L234I | P142A, S283G |
| >99_R1149| codons 1-288 FLDGIDKAQEEHERYHSNWRTMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKVIHTDNGSN FTSAAVKAACWWANVRQEFGIAYNPQSQGVVESMNKELKRIIGQVREQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, E35D, M36I, R41K, H69K, L89M |
| >99_R1149| codons 1-99 PQITLWQRPLVTVKIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| I5V, E6D, V35T, T39K, K43E, K122E, D123S, S162C, K173T, Q174E, D177E, I178M, T200A, Q207A, R211S, V245E, E291D, V292I, I293V, K311R, E312I, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, E399D, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, L517V, S519N, Q524E, E529D, A534S, A554S |
| >99_R1149| codons 1-560 PISPVDTVPVKLKPGMDGPKVKQWPLTEEKIKALTEICKEMEEEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRTENPEMVI YQYMDDLYVGSDLEIGQHRAKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTDIVPLTEEAE LELAENREILRIPVHGVYYDPSKDLVAEVQKQGQDQWTYQIYQEPFKNLKTGKYARKRSA HTNDVRQLTEVVQKIATESIVIWGKTPKFRLPIQRETWDTWWMEYWQATWIPEWEFVNTP PLVKLWYQLEKDPIVGAETFYVDGAASRETKLGKAGYVTDRGRQKVVSLTETTNQKTELH AIHLALQDSGSEVNIVTDSQYALGIIQAQPDKSESEVVNQIIEELIKKDKVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Watanaveeradej, V | Molecular epidemiology of HIV type 1 in preparation for a phase III prime-boost vaccine trial in Thailand and a new approach to HIV type 1 genotyping. | ARHR, 2006 |