Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 00TH_C4118 | 00_C4118 | Thailand | 2000 | HIV1 | CRF01_AE | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| K14R, A21T, V32I, I72V, T112V, T124A, T125A, G134N, I135V, K136R, V165I, D167E, V201I, L234I | S283G |
| >00_C4118| codons 1-288 FLDGIDKAQEEHERYHSNWRTMASDFNLPPVIAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKVIHTDNGSN FTSAAVKAACWWANVRQEFGIPYNPQSQGVVESMNKELKKIIGQIREQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I | L10I, I13V, I15V, E35N, M36I, R41K, L63P, G68E, H69K, L89M |
| >00_C4118| codons 1-99 PQITLWQRPIVTVKVGGQLKEALLDTGADDTVLENINLPGKWKPKIIGGIGGFIKVRQYD QIPIEICEKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| E6D, K11T, V35T, T39K, K43E, K122E, D123S, I135T, K173R, Q174K, D177E, I178M, T200I, Q207A, R211S, I244V, V245E, T286A, E291D, V292I, I293V, K311R, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, T403M, E432D, V435A, R463K, D471E, Q480H, H483Y, L491S, K512R, L517V, S519N, Q524E, A534S, A554S |
| >00_C4118| codons 1-560 PISPIDTVPVTLKPGMDGPKVKQWPLTEEKIKALTEICKEMEEEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRRKNPEMVI YQYMDDLYVGSDLEIGQHRIKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPVELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVPLTEEAE LELAENREILRTPVHGVYYDPSKDLVAEVQKQGQDQWTYQIYQEPFKNLKTGKYARKRSA HTNDVRQLTEVVQKIATESIVIWGKTPKFRLPIQRETWEAWWMEYWQATWIPEWEFVNTP PLVKLWYQLEKDPIAGAETFYVDGAANRETKLGKAGYVTDRGKQKVVSLTETTNQKTELH AIYLALQDSGSEVNIVTDSQYALGIIQAQPDRSESEVVNQIIEELIKKEKVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Watanaveeradej, V | Molecular epidemiology of HIV type 1 in preparation for a phase III prime-boost vaccine trial in Thailand and a new approach to HIV type 1 genotyping. | ARHR, 2006 |