Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MSA4070 | MSA4070 | Kenya | 2000 | HIV1 | A | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| E11D, K14R, A21T, V31I, I72V, T112V, I113V, T124A, T125A, G134N, K136Q, V201I, L234I, I268L | S283G |
| >MSA4070| codons 1-288 FLDGIDKAQEDHERYHSNWRTMASDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKVVHTDNGSN FTSAAVKAACWWANIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKILRDYGKQMAGDDCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, E35D, M36I, R41K, K45R, R57K, H69K, L89M |
| >MSA4070| codons 1-99 PQITLWQRPLVTVKIGGQLKEALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVKQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K11T, V35T, V60I, K122E, D123N, I135T, I142V, K173S, Q174K, D177E, V179I, Q207A, R211S, V245M, E248D, D250E, K281R, T286A, E291D, V292I, I293V, P294T, E312D, I326V, G335D, M357K, G359S, K366R, T369A, A371V, I375V, T377M, A400T, T403M, E404D, E432D, V435L, D471E, Q480H, H483L, L491S, K512R, S519N, Q524K, K527G, E529D, V531I, A534S, A554S |
| >MSA4070| codons 1-560 PISPIETVPVTLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPEIII YQYMDDLYVGSDLEIGQHRTKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIMLPDKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCRLLRGAKALTDIVTLTEEAE LELAENREILKDPVHGVYYDPSKDLVAEIQKQGQDQWTYQIYQEPFKNLKTGKYARKRSA HTNDVRQLAEVVQKVAMESIVIWGKTPKFKLPIQKETWETWWMDYWQATWIPEWEFVNTP PLVKLWYQLEKDPILGAETFYVDGAANRETKLGKAGYVTDRGRQKVVSLTETTNQKTELH AILLALQDSGSEVNIVTDSQYALGIIQAQPDRSESELVNQIIEKLIGKDKIYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Dowling, WE | Forty-one near full-length HIV-1 sequences from Kenya reveal an epidemic of subtype A and A-containing recombinants. | AIDS, 2002 |