Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| KNH1209 | KNH1209 | Kenya | 2000 | HIV1 | A | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| L2I, E11D, K14R, A21T, V31I, I72V, T112V, I113V, T124A, T125A, K136Q, D167E, V201I, L234V | S283G |
| >KNH1209| codons 1-288 FIDGIDKAQEDHERYHSNWRTMASDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKVVHTDNGSN FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPVWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, I13V, K14R, E35D, M36I, N37D, R41K, R57K, H69K, K70R, L89M |
| >KNH1209| codons 1-99 PQITLWQRPIVTVRIGGQLKEALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFIKVKQYD QILIEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K11E, V35T, K49R, V60I, D121H, D123S, I135T, T165I, K173S, Q174K, D177E, V179I, T200A, Q207A, R211S, V245Q, D250E, K275R, V276I, T286A, E291D, V292I, I293V, P294T, E312N, I326V, G335E, M357K, G359S, A360T, T369A, A371V, I375V, T377M, A400T, T403M, E404D, Y405H, E432D, V435M, E449Q, T470P, D471E, Q480Y, L491S, K512R, L517I, S519N, K527E, E529D, K530R, A534S, A554S |
| >KNH1209| codons 1-560 PISPIETVPVELKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL HKSFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMIKILEPFRSKNPEIII YQYMDDLYVGSDLEIGQHRAKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKESWTVNDIQKLVGKLNWASQIYAGIRIKQLCKLLRGAKALTDIVTLTEEAE LELAENREILKNPVHGVYYDPSKDLVAEIQKQGQEQWTYQIYQEPFKNLKTGKYARKRST HTNDVKQLAEVVQKVAMESIVIWGKTPKFKLPIQKETWETWWMDHWQATWIPEWEFVNTP PLVKLWYQLEKDPIMGAETFYVDGAANRQTKLGKAGYVTDRGRQKVVSLPETTNQKTELY AIHLALQDSGSEVNIVTDSQYALGIIQAQPDRSESEIVNQIIEQLIEKDRVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Dowling, WE | Forty-one near full-length HIV-1 sequences from Kenya reveal an epidemic of subtype A and A-containing recombinants. | AIDS, 2002 |