Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| KER2009 | KER2009 | Kenya | 2000 | HIV1 | A | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| K14R, A21T, T112V, I113V, T124A, T125A, K136Q, D167E, V201I, I220V, Y227F, D256E | S283G |
| >KER2009| codons 1-288 FLDGIDKAQEEHERYHSNWRTMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKVVHTDNGSN FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKVQNFRVYFRDSRDPLWKGPAK LLWKGEGAVVIQDNSEIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, I13V, K20R, E35D, M36I, N37D, R41K, K45R, R57K, H69K, K70R, L89M |
| >KER2009| codons 1-99 PQITLWQRPIVTVKIGGQLREALLDTGADDTVLEDIDLPGKWKPRMIGGIGGFIKVKQYD QILIEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, V60I, K122E, D123S, I135T, E138A, S162C, K173S, Q174K, V179I, Q207A, R211S, F214L, D250E, A272P, T286A, E291D, V292I, I293V, P294T, E312D, D324E, G335D, M357K, G359S, K366R, A371V, I375V, A376V, T377L, A400T, T403M, E404D, E432D, R448K, D471E, Q480H, H483Y, L491S, K512R, L517I, S519N, Q524K, K527E, E529D, V531I, A534S, A554S |
| >KER2009| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNATPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRSKNPDIII YQYMDDLYVGSDLEIGQHRTKIEELRAHLLSWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVTLTEEAE LELAENREILKDPVHGVYYDPSKELIAEIQKQGQDQWTYQIYQEPFKNLKTGKYARKRSA HTNDVRQLTEVVQKVVLESIVIWGKTPKFKLPIQKETWETWWMDYWQATWIPEWEFVNTP PLVKLWYQLEKDPIVGAETFYVDGAANKETKLGKAGYVTDRGRQKVVSLTETTNQKTELH AIYLALQDSGSEVNIVTDSQYALGIIQAQPDRSESEIVNQIIEKLIEKDKIYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Dowling, WE | Forty-one near full-length HIV-1 sequences from Kenya reveal an epidemic of subtype A and A-containing recombinants. | AIDS, 2002 |