Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| BOL137 | BOL137 | Bolivia | 1999 | HIV1 | F | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| V54I, G163R | E11D, V37I, I72V, I84L, L101I, S119T, T124A, T125A, K136Q, V201I, A205S, K211R, T218I, L234V, D256E | S283G |
| >BOL137| codons 1-288 FLDGIDKAQEDHEKYHSNWRAMASDFNLPPVVAKEIIASCDKCQLKGEAMHGQIDCSPGI WQLDCTHLEGKVILVAVHVASGYLEAEVIPAETGQETAYFILKLAGRWPVKTIHTDNGTN FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIRQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIISTDIQTRELQKQIIKIQNFRVYYRDSRDPVWKGPAK LLWKGEGAVVIQDNSEIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12E, I15V, E35D, M36I, R57K, Q61N, L63R, K70E, V82I, I93L |
| >BOL137| codons 1-99 PQITLWQRPLVEIKVGGQLKEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVKQYD NIRIEICGHEAIGTVLVGPTPINIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K102R, I135V, I178M, R211K, A272P, K281R, E297K, K311R, S322T, A371V, A376T, K390R, Q394L, E399D, A400T, K431T, V435T, A446S, L452K, R461K, D471E, T477A, Q480H, H483Q, L491S, E492Q, K512R, S519N, A534S, V559I |
| >BOL137| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKRKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDMVI YQYMDDLYVGSDLEIGQHRTKIEELRQHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGTKALTEVIPLTKEAE LELAENREILREPVHGVYYDPTKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGA HTNDVKQLTEVVQKITTESIVIWGKTPKFRLPILKETWDTWWTEYWQATWIPEWEFVNTP PLVKLWYQLETEPITGAETFYVDGASNRETKKGKAGYVTDKGRQKVVSLTETTNQKAELH AIQLALQDSGSQVNIVTDSQYALGIIQAQPDRSESELVNQIIEQLIKKEKVYLSWVPAHK GIGGNEQVDKLVSAGIRKIL |
References
| Author | Title | Citation |
| Carr, JK | Diverse BF recombinants have spread widely since the introduction of HIV-1 into South America. | AIDS, 2001 |