Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| BOL122 | BOL122 | Bolivia | 1999 | HIV1 | B | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| E10D, M22I, E35Q, S39N, L45V, L101I, T124N, T125A, I135V, K156N |
| >BOL122| codons 1-288 FLDGIDKAQDEHEKYHSNWRAIASDFNLPPVVAKQIVANCDKCQVKGEAMHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKTIHTDNGSN FTSNAVKAACWWAGVKQEFGIPYNPQSQGVVESMNNELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12K, I15V, E35D, R41K, R57K, L63P |
| >BOL122| codons 1-99 PQITLWQRPLVKIKVGGQLKEALLDTGADDTVLEDMNLPGKWKPKMIGGIGGFIKVKQYD QIPIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K101R, K122E, I135T, S162C, R211K, F214L, E248H, A272P, I329L, Q334E, Y342F, E344D, M357A, R358K, V365I, A400T, E432D, V435E, A437V, D460N, H483Y, L491P, K512R, L517I, I556V |
| >BOL122| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLRKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELRQHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPHKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVIPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAELQKQGEGQWTYQIFQDPFKNLKTGKYARAKGA HTNDIKQLTEAVQKIATESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTP PLVKLWYQLEKDPIEGVETFYVDGAANRETKLGKAGYVTNRGRQKVVSLTDTTNQKTELQ AIYLALQDSGPEVNIVTDSQYALGIIQAQPDRSESEIVSQIIEQLIKKEKVYLAWVPAHK GIGGNEQVDKLVSAGVRKVL |
References
| Author | Title | Citation |
| Carr, JK | Diverse BF recombinants have spread widely since the introduction of HIV-1 into South America. | AIDS, 2001 |