Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pt193 | 04SK162B1 | South Africa | 2004 | HIV1 | A | Plasma | MC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| E11D, E13D, A21T, V31I, G106A, K111R, T112V, T124A, T125A, G134N, I135V, K136Q, V201I, P233S, L234V, K240R, D256E |
| >04SK162B1| codons 1-288 FLDGIDKAQEDHDKYHSNWRTMASDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFLLKLAARWPVRVIHTDNGSN FTSAAVKAACWWANVQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDSVWKGPAR LLWKGEGAVVIQDNSEIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, E35D, M36I, R41K, H69K, L89M |
| >04SK162B1| codons 1-99 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| E6K, V35T, K122E, I135T, I142V, K173S, I202V, R211S, F214L, V245Q, E248D, A272S, K277R, T286A, E291D, I293V, E312N, S322A, G335D, R356K, M357K, G359S, A371V, I375V, A376V, A400T, T403M, Y405C, E432D, V435L, S468P, D471E, Q480H, H483Y, L491P, K512R, S515A, L517I, S519N, Q524K, K527E, K530R, A534S, A554S, K558R | K13R |
| >04SK162B1| codons 1-560 PISPIKTVPVKLRPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSQNPDIVI YQYMDDLYVGSDLEIGQHRTKVEELRQHLLSWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYSGIKVRQLCKLLRGAKALTDVVPLTEEAE LELAENREILKNPVHGVYYDPAKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKKRSA HTNDVKQLTEVVQKVVTESIVIWGKTPKFKLPIQKETWETWWMECWQATWIPEWEFVNTP PLVKLWYQLEKDPILGAETFYVDGAANRETKLGKAGYVTDRGRQKVVPLTETTNQKTELH AIYLALQDSGPEVNIVTDSQYALGIIQAQPDRSEAEIVNQIIEKLIEKERVYLSWVPAHK GIGGNEQVDKLVSSGIRRVL |
References
| Author | Title | Citation |
| Rousseau, CM | Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. | J Virol Methods, 2006 |