Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pt23 | 03PS045MB2 | South Africa | 2003 | HIV1 | B | Plasma | MC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| E11D, E13D, R20K, A21T, D41G, I72V, K111R, T124A, M154L, V165I, D207G, K211R, T218I, S230N |
| >03PS045MB2| codons 1-288 FLDGIDKAQEDHDKYHSNWKTMASDFNLPPVVAKEIVASCGKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVRTIHTDNGSN FTSATVKAACWWAGIKQEFGIPYNPQSQGVVESLNKELKKIIGQIRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIVDIIATGIQTRELQKQIIKIQNFRVYYRDNRDPLWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| E35D, N37S, R57K, L63P, K70R, V77I, I93L |
| >03PS045MB2| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEDMSLPGRWKPKMIGGIGGFIKVKQYD QIPIEICGHRAIGTVLIGPTPVNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K173N, D177E, Q207G, R211K, V245M, A272P, V276I, I293V, I329L, Q334L, G335N, M357T, R358K, S379G, T386I, K390R, E396D, A400T, V435I, L452R, D460N, R461K, S468P, L491P, K512T, V518A, S519N |
| >03PS045MB2| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRNQNPEIVI YQYMDDLYVGSDLEIGQHRTKIEELRGHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYPGIKIKQLCKLLRGTKALTEVVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAELQKQGLNQWTYQIYQEPFKNLKTGKYARTKGA HTNDVKQLTEAVQKIATEGIVIWGKIPKFRLPIQKDTWETWWTEYWQATWIPEWEFVNTP PLVKLWYQLEKEPIIGAETFYVDGAANRETKRGKAGYVTNKGRQKVVPLTDTTNQKTELQ AIHLALQDSGPEVNIVTDSQYALGIIQAQPDTSESELANQIIEQLIKKEKVYLAWVPAHK GIGGNEQVDKLVSAGIRKVL |
References
| Author | Title | Citation |
| Rousseau, CM | Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. | J Virol Methods, 2006 |