Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pt63 | 03PS119MB1 | South Africa | 2003 | HIV1 | A | Plasma | MC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| K14R, S17T, V31I, I72V, G106A, T112V, T124A, T125A, G134N, I135V, K136Q, V201I, L234I, K240R | S283G |
| >03PS119MB1| codons 1-288 FLDGIDKAQEEHERYHTNWRAMASDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAARWPVKVIHTDNGSN FTSAAVKAACWWANVQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAR LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, E35D, M36I, R41K, L63Q, H69K, L89M |
| >03PS119MB1| codons 1-99 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QIQIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K11T, K20R, V35T, V60I, K122E, D123N, I135T, E138A, I142V, K173A, Q174R, D177G, G196E, I202V, Q207A, R211S, F214L, V245Q, A272P, K277R, E291D, V292I, I293V, Q334D, R356K, G359T, K366R, T369V, Q373H, T377L, K390R, A400I, E404D, E432D, V435L, L452M, V466I, V467I, T470S, D471E, Q480H, H483K, L491P, S519N, K530R, A534S, A554S |
| >03PS119MB1| codons 1-560 PISPIETVPVTLKPGMDGPRVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSTNNATPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRARNPGIVI YQYMDDLYVGSDLEIEQHRTKVEELRAHLLSWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGDGQWTYQIYQEPFKNLKTGKYAKMRTA HTNDVRQLVEAVHKIALESIVIWGKTPKFRLPIQKETWEIWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKDPILGAETFYVDGAANRETKMGKAGYVTDRGRQKIISLSETTNQKTELH AIKLALQDSGPEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKERVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Rousseau, CM | Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. | J Virol Methods, 2006 |